4,5-Cis-didehydro-PGF.sub.1.sub..alpha. analogs

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260211R, 260240R, 2602472R, 260268R, 26029365, 2603262, 2603732R, 2604299, 260439R, 260448R, 2604488R, 2605011, 26050115, 26050117, 2605012, 260514D, 424305, 424317, C07C 6138, C07C 6974

Patent

active

039338894

ABSTRACT:
This invention is a group of 4,5-didehydro PG.sub.1 (prostaglandin-type) analogs having variable chain length, branching and fluoro substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

REFERENCES:
patent: 3711515 (1973-01-01), Kelly
March, Organic Chemistry, pp. 662-663, (1969).
Fieser et al., Reagents for Organic Synthesis, p. 671, (1967).

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