4,5-Cis-didehydro-PGF.sub.1 compounds

Details 4,5-Cis-didehydro-PGF.sub.1 compounds 4,5-Cis-didehydro-PGF.sub.1 compounds

1974-02-07

1976-05-04

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240R, 260211R, 260242, 260268R, 2602936S, 2603262, 2603452, 260410, 2604299, 260439R, 260448R, 2604488R, 260488R, 2605011, 26050115, 26050117, 2605012, 260514D, 424305, 424317, C07C 6974, C07C 6130

Patent

active

039548350

ABSTRACT:
This invention is a group of 4,5-didehydro and 4,5,17,18-tetradehydro PG.sub.1 (prostaglandin-type) compounds, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

REFERENCES:
patent: 3711515 (1973-01-01), Kelly
March Advanced Organic Chemistry, pp. 662-663, (1968).
Fieser et al., Organic Reagents, p. 671 (1967).
Van Dorp, N. Y. Acad. of Sci., 180, pp. 184-186 (1970).

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