4,5-Cis-didehydro-PGF.sub.1 analogs

Details 4,5-Cis-didehydro-PGF.sub.1 analogs 4,5-Cis-didehydro-PGF.sub.1 analogs

1975-11-07

1977-01-18

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260488R, 2605011, 260514D, C07C17700

Patent

active

040039463

ABSTRACT:
This invention is a group of 4,5-didehydro PG.sub.1 (prostaglandin-type) analogs having variable chain length, branching and fluoro substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

REFERENCES:
patent: 3932479 (1976-01-01), Bernady et al.
patent: 3948981 (1976-04-01), Pike et al.

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