4,5-Cis-didehydro-PGE.sub.1 analogs

Details 4,5-Cis-didehydro-PGE.sub.1 analogs 4,5-Cis-didehydro-PGE.sub.1 analogs

1975-11-07

1977-12-13

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260514D, C07C17700

Patent

active

040630269

ABSTRACT:
This invention is a group of 4,5-didehydro PG.sub.1 (prostaglandin-type) analogs having variable chain length, branching and fluoro substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

REFERENCES:
patent: 3816393 (1974-06-01), Hayashi et al.
Van Dorp: Annals, N.Y., Acad. of Sci. 180, p. 185, (1971).

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