4,5-Cis-didehydro-PGA.sub.1 analogs

Details 4,5-Cis-didehydro-PGA.sub.1 analogs 4,5-Cis-didehydro-PGA.sub.1 analogs

1975-11-07

1976-10-12

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260488R, 260514D, C07C17700

Patent

active

039857875

ABSTRACT:
This invention is a group of 4,5-didehydro PG.sub.1 (prostaglandin-type) analogs having variable chain length, branching and fluoro substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

REFERENCES:
van Dorp, Annals of N.Y. Acad. Sci., 180, 181, 1971.

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