4,5-bis(aryl) 4H-1,2,4-triazoles derivatives and analgesic use

Details 4,5-bis(aryl) 4H-1,2,4-triazoles derivatives and analgesic use 4,5-bis(aryl) 4H-1,2,4-triazoles derivatives and analgesic use

1992-05-04

1994-01-11

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5482672, 5482678, 5482686, A61K 3141, C07D24908

Patent

active

052781801

ABSTRACT:
A novel process for the preparation of 4H-1,2,4-triazoles in their racemic or optically active forms of the formula ##STR1## wherein the compounds have analgesic activity.

REFERENCES:
patent: 4512997 (1985-04-01), Meier et al.
Reimlinger et al, "Cyclocondensation of open-chain, etc." CA 74: 87898y (1971).
Roussel-Uclaf, "4H-1,2,4-Triazole derivatives, etc" CA 97: 92286b (1982).

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