4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid a

Details 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid a 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid a

1993-09-16

1995-03-28

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142285, 5142345, 514253, 514303, 546118, 544 584, 544127, 544362, A61K 31435, C07D47104

Patent

active

054017360

ABSTRACT:
Disclosed herein are 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid amide derivatives having a high antagonistic activity against angiotensin II and a high specificity to angiotensin II receptors, intermediates for preparing the derivatives, and antagonists against angiotensin II comprising the derivatives.

REFERENCES:
patent: 5091390 (1992-02-01), Ardecky et al.
C. J. Blankley et al "Synthesis and structure-activity . . . " Journal of Medicinal Chemistry, vol. 34, 1991, Washington, US, pp. 3248-3260.
J. C. Hodges "Regiospecific synthesis of 3-substituted . . . " Synthesis, No. 1, 1987, Stuttgard De, pp. 20-24.
K. Barlos et al "Eine einfache synthese . . . " Liebigs Annalen Der Chemie, 1989, Weinheim DE, pp. 387-388.
R. J. Howard et al "Inhibitory effects of . . . " Chemical Abstracts, vol. 105, No. 23, 1986, Columbus, Ohio US, Abstract #205895d, p. 325. Abstract Only.
G. C. Stelakatos et al "On the trityl method for . . . " Journal of the American Chemical Society, vol. 81, 1959, Washington, D.C. pp. 2884-2887.
M. Del Mar Sanchez-Sanchez et al "The Pictet-Spengler reaction . . . " Chemical Abstracts, vol. 118, No. 19, 1993, Columbus, Ohio US, Abstract #192077e, 992. Abstr. Only.
Biorganic & Medicinalal Chemistry Letters, vol. 1, No. 12, pp. 711-716, 1991 Middlemiss et al "Bromobenzofurans: A new Class of Potent, Non-peptide etc".

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