4-(4-imidazolyl) piperidines substituted at position 1, their pr

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514316, 546186, 546187, 546208, 546209, 546210, A61K 31445, C07D40104, C07D40514

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052907902

ABSTRACT:
The compounds correspond to the general formula ##STR1## in which R.sub.1 represents a hydrogen atom or a group --COR.sub.2, in which R.sub.2 represents a benzene ring, cyclopentylmethyl, cyclohexylmethyl, cyclopentylethyl or cyclohexylethyl groups or cyclopentylamine, cyclohexylamine or phenylamine, chlorophenylamine or dichlorophenylamine groups; R represents a hydrogen atom or a group COR.sub.3, in which R.sub.3 represents an aliphatic group, a cyclane or benzene ring-system, a group a group (CH.sub.2).sup.m R.sub.4, a group --CH.dbd.CHR.sub.8 or a secondary amine group --NH(CH.sub.2).sub.n R.sub.g ; R also represents a hydroxyalkenyl group: ##STR2##

REFERENCES:
patent: 4431653 (1984-02-01), Wei et al.
patent: 4675403 (1987-06-01), Abou-Gharbia
patent: 4707487 (1987-11-01), Arrang et al.
patent: 5059601 (1991-10-01), Salimbeni
Chemical Abstracts, vol. 80, No. 15, p. 389, No. 82801a (1985).

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