4,4,5,5-Tetradehydro-11-deoxy-PGE.sub.1 analogs

Details 4,4,5,5-Tetradehydro-11-deoxy-PGE.sub.1 analogs 4,4,5,5-Tetradehydro-11-deoxy-PGE.sub.1 analogs

1976-11-04

1977-08-16

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260408, 260413, 260468D, 260514D, C07C17700

Patent

active

040426084

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which there is a triple bond between C-5 and C-6 or C-4 and C-5. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
patent: 3933889 (1976-01-01), Magerlin

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