4-[4-[4-[4-[[2-(2,4-difluoro phenyl)-2-(1H-azolylmethyl)-1,3-dio

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544366, 544370, A61K 31495, C07D40314

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active

049161342

ABSTRACT:
4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]m ethoxy]phenyl]-1-piperazinyl]phenyl]triazolones, their pharmaceutically acceptable acid addition salts and stereoisomeric forms having improved antimicrobial properties, compositions containing the same, and methods of inhibiting and/or eliminating the development of fungi and bacteria in warm-blooded animals suffering from diseases caused by these fungi and/or bacteria.

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patent: 4368200 (1983-01-01), Heeres et al.
patent: 4404216 (1983-09-01), Richardson
patent: 4490530 (1984-12-01), Heeres et al.
patent: 4791111 (1988-12-01), Heeres et al.
Barriese, Hospital Therapy, (1988), "Iraconazole and Fluconazole", pp. 68-83.
Janssen et al., A Postgraduate Symposium: Dermatology Update, "Antifungal Therapy of the Future".

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