4-(3-Iodopropargyloxy) pyrimidine derivatives

Details 4-(3-Iodopropargyloxy) pyrimidine derivatives 4-(3-Iodopropargyloxy) pyrimidine derivatives

1981-06-15

1983-05-17

Coughlan, Jr., Paul M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544319, 544320, C07D23947, C07D23956

Patent

active

043841180

ABSTRACT:
4-(3-Iodopropargyloxy) pyrimidine derivatives of the general formula ##STR1## wherein R.sub.1 is selected from among a halogen atom, an amino group, a C.sub.1 -C.sub.4 alkylamino or a C.sub.1 -C.sub.4 alkylthio group, and R.sub.2 is selected from among a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.4 alkyl group or a C.sub.1 -C.sub.4 alkoxy group, are disclosed. The described compounds are prepared by reacting a 4-halopyrimidine with propargyl alcohol and iodinating the resultant product in the 3 position of the propargyl chain.

REFERENCES:
patent: 3907797 (1975-09-01), Budesinsky et al.
patent: 3980781 (1976-09-01), Snell et al.

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