4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and deriva

Details 4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and deriva 4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and deriva

1982-11-08

1985-03-19

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546278, C07D40112, A61K 31415

Patent

active

045059187

ABSTRACT:
4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and derivatives and acid addition salts thereof are selective central-adrenergic receptor agonists and thereby useful as antihypertensives.

REFERENCES:
patent: 3907816 (1975-09-01), Winkelmann et al.
patent: 4046896 (1977-09-01), Winkelmann et al.
patent: 4078063 (1978-03-01), Lumma et al.
patent: 4376772 (1983-03-01), Saari et al.
patent: 4381302 (1983-04-01), Huff et al.
patent: 4442103 (1984-04-01), Saari
patent: 4456604 (1984-06-01), Saari
Ser. No. 439,697, by Huff et al.
Ser. No. 436,753, by Saari.

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