Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-07-31
1990-08-07
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549 23, C07D49504, A61K 3138
Patent
active
049468596
ABSTRACT:
4-(2-Methyl-2-hydroxypropylamino)-5,6-dihydrothieno[2,3-b]thiopyran-2-sulfo namide-7,7-dioxide is a major mammalian metabolite of 4-(2-methylpropylamino)-5,6-dihydrothieno[2,3-b]thiopyran-2-sulfonamide-7, 7-dioxide and is itself an active carbonic anhydrase inhibitor useful in the treatment of ocular hypertension by topical administration.
REFERENCES:
patent: 4677115 (1987-06-01), Baldwin et al.
patent: 4797413 (1989-01-01), Baldwin et al.
Hoffman, Jr. Jacob M.
Lee Ling L.
Varga Sandor L.
Zacchei Anthony G.
DiPrima Joseph F.
Haley Jacqueline
Lee Mary C.
Merck & Co. , Inc.
Nicholson William H.
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