4-(2-Imidazolin-2-yl) aminopyrazoles

Details 4-(2-Imidazolin-2-yl) aminopyrazoles 4-(2-Imidazolin-2-yl) aminopyrazoles

1976-10-19

1978-08-22

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Live hair or scalp treating compositions

Shaving preparation

548316, 548320, 548358, 260307F, 424 70, 424272, 424273P, C07D40312, A61K 715

Patent

active

041089820

ABSTRACT:
Physiologically-active and pharmaceutically-acceptable 4-aminopyrazoles of each of the formulae ##STR1## wherein each of R.sup.1, R.sup.2 and R.sup.3 is, independently, e.g., a hydrogen atom (--H), aliphatic hydrocarbyl, alicyclic hydrocarbyl, phenyl, substituted phenyl, phenalkyl or nuclearly-substituted phenalkyl.
And their pharmacologically-acceptable acid-addition salts are synthesized by known procedures from available starting materials or from compounds which are made by analogy procedures from known compounds. The subject 4-aminopyrazoles and their pharmacologically-acceptable acid-addition salts are prepared in the form of medicament compositions and used as diuretics, saluretics and/or antihypertensives.

REFERENCES:
patent: 3954757 (1976-05-01), Arya et al.
patent: 3979408 (1976-09-01), Trani
Pollak et al., Monatshefte fur Chemie 1972, vol. 103, pp. 1591-1603.
Verge et al., Chem. Abst. 1975, vol. 83, No. 10079k.

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