4-(2-furoyl)aminopiperidine compound useful as therapeutic...

Details 4-(2-furoyl)aminopiperidine compound useful as therapeutic... 4-(2-furoyl)aminopiperidine compound useful as therapeutic...

2004-05-06

2009-10-13

Anderson, Rebecca L (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S318000

Reexamination Certificate

active

07601843

ABSTRACT:
There are provided compounds represented by the following general formula (I):[where R1is 5-methylpyridin-2-yl, p-tolyl or mesityl, R2is one of the following general formulas (II)-(IX):(where R3is C1-C4 alkyl, R4is H or C1-C4 alkyl, R5is H, 3-pyridylmethyl or 4-pyridylmethyl, and R6is 2,4-dihydroxybenzyl, 3-pyridylmethyl or 4-pyridylmethyl), or when R1is mesityl, R2is the following formula (X)],and pharmaceutically acceptable salts thereof. The compounds exhibit pruritus-inhibiting action, and are useful for prevention or of itching and pruritus caused by reaction against insect-inflicted wounds, reaction against environmental allergens, skin infections or external parasite infections, or caused to renal dialysis patient.

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