Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-06-04
1986-06-03
Daus, Donald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
514418, C07D20938
Patent
active
045931062
ABSTRACT:
4-[2-(Dialkylamino)ethyl]-7-hydroxyisatins are prepared by internal condensation of an oxime followed by removal of protecting groups. The compounds are D.sub.2 -agonists and, thereby, have anti-hypertensive activity. A species of the group is 4-[2-(di-n-propylamino)ethyl]-4-hydroxyisatin.
REFERENCES:
patent: 4314944 (1982-02-01), Huffman et al.
patent: 4395559 (1983-07-01), Fothergill
patent: 4414224 (1983-11-01), Huffman
Stringer Orum D.
Weinstock Joseph
Wilson James W.
Benson Robert
Daus Donald G.
Lourie Alan D.
Marlino Joseph A.
SmithKline Beckman Corporation
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