4,13-dioxabicyclo[8.2.1]tridecenone compounds and pharmaceutical

Details 4,13-dioxabicyclo[8.2.1]tridecenone compounds and pharmaceutical 4,13-dioxabicyclo[8.2.1]tridecenone compounds and pharmaceutical

1992-12-23

1995-05-23

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 72, 536 181, A61K 3170, C07H 1708

Patent

active

054182247

ABSTRACT:
Ring-contracted N-demethyl-N-isopropylerythromycin A derivatives with gastrointestinally effective motilin-agonistic properties, a method for preparing such compounds, and pharmaceutical compositions containing them.

REFERENCES:
patent: 3725385 (1973-04-01), Freiberg
patent: 4920102 (1990-04-01), Gidda et al.
patent: 5106961 (1992-04-01), Kirst et al.
Tsuzuki et al., Chem. Pharm Bull., vol. 37, No. 10, pp. 2687-2700 (1989).
Kibwage et al., J. Antibiotics, vol. 40, No. 1, pp. 1-6 (1987).
European Search Report, The Hague, completed Mar. 31, 1993.

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