Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-12-07
1987-07-07
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540363, 540364, 540355, C07D20508, C07D40312, A61K 31395, A61K 31495
Patent
active
046787828
ABSTRACT:
A monocyclic .beta.-lactam antibiotic having a formamido substitutent at the 3S-position, including compounds of the formula (I): ##STR1## and salts thereof wherein R is --SO.sub.3 H; --PO(OH)Y wherein Y is C.sub.1-6 alkoxy, hydroxy, aryloxy, C.sub.1-6 alkyl or aryl; ##STR2## wherein Z represents C.sub.1-6 alkyl or aryl; ##STR3## wherein Z.sup.1 and Z.sup.2 may be the same or different and each represents hydrogen, C.sub.1-6 alkyl, aryl, amino or C.sub.1-6 alkoxy, or Z.sup.1 and Z.sup.2 together form the residue of a heterocyclic ring; --OSO.sub.3 H; or ##STR4## where X is hydrogen or hydroxy; R.sup.1 is an amino, protected amino or carboxylic acylamino group, and R.sup.2 and R.sup.3 are independently selected from hydrogen or a hydrocarbon group of 1 to 18 carbon atoms.
REFERENCES:
Chemical Abstracts, vol. 91, 107770g (1979).
Chemical Abstracts, vol. 97, 216126w (1982).
Chemical Abstracts 1977-1981 General Subject Index, see `Substitution Reaction-Heteroarylation`.
Synthesis (Intl. Jour. of Methods in Synthetic Organic Chemistry), 1979, No. 11 (Nov.), p. 841 and contents page enclosed.
Annual Reports on the Progress of Chemistry, vol. 77, 1980, Section B, (Organic Chemistry), p. 181, T. M. Cresp (University College, London).
Nomenclature of Organic Chemistry--Sections A,B,C,D,E,F&H (1979 Edition), IUPAC, J. Rigaudy and S. P. Klesney, Pergamon Press.
Finch Stephen C.
Pearson Michael J.
Ponsford Roger J.
Beecham Group p.l.c.
Berch Mark L.
LandOfFree
3S-formamido azetidinone antibacterial agents, their preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 3S-formamido azetidinone antibacterial agents, their preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3S-formamido azetidinone antibacterial agents, their preparation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1663042