Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1997-10-17
2000-12-19
Qazi, Sabiha N.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514557, 562469, C07C 6100, A61K 3119
Patent
active
061628298
ABSTRACT:
The present invention relates to non-psychoactive derivatives of tetrahydro-cannabinol, which exhibit anti-inflammatory, analgesic and leukocyte antiadhesion activities. The invention includes novel derivatives of (3R,4R)-.DELTA..sup.8 -tetrahydrocannabinol-11-oic acids [hereinafter referred to as (3R,4R)-.DELTA..sup.8 -THC-11-oic acid], as well as pharmaceutical compositions containing the (3R,4R)-.DELTA..sup.8 -THC-11-oic acid derivatives. The invention further covers methods of administering the novel derivatives and pharmaceutical compositions as therapeutic agents in the treatment of pain and tissue inflammation. Non-psychoactive derivatives of .DELTA..sup.8 -THC-11-oic acid are described which have analgesic and anti-inflammatory properties.
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Atlantic Pharmaceuticals, Inc.
Qazi Sabiha N.
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