Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1983-06-29
1985-10-29
Raymond, Richard L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
514213, 514906, C07D22316
Patent
active
045499888
ABSTRACT:
There is presented 3H-2-benzazepines and 4,5-dihydro-3H-2-benzazepines of the formula ##STR1## wherein X is hydrogen, chloro or bromo, Y is hydrogen, fluoro or chloro with the proviso that X and Y cannot both be hydrogen and R.sub.1 is selected from the group consisting of hydrogen, bromo, chloro, iodo, a radical of the formula ##STR2## and a radical of the formula ##STR3## wherein R.sub.2 is hydrogen, phthalimido, lower alkyl, hydroxy, amino, monoalkylamino and dialkylamino and R.sub.3 is hydroxy, phthalimido or amino with the proviso that where R.sub.1 is other than hydrogen then the bonding at the 4,5-position is unsaturated,
and the pharmaceutically acceptable salts thereof.
REFERENCES:
Padwa et al., J.A.C.S., 97(16), 4682-91.
Fryer Rodney I.
Trybulski Eugene J.
Walser Armin
Hoffman Frank P.
Hoffmann-La Roche Inc.
Leon Bernard S.
Raymond Richard L.
Saxe Jon S.
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