Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1995-03-01
1998-07-14
Sidberry, Hazel F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242341, 4241841, 4241851, 530350, 435 691, 435 693, 435 711, C07K 1420, A61K 3902, C12P 2106
Patent
active
057800413
ABSTRACT:
The present invention relates to antigenic proteins specific to Borrelia burgdorferi which have a molecular weight of 28 kDa or 39 kDa as determined by SDS-PAGE and are reactivity with Lyme borreliosis serum or fragments thereof and to the corresponding DNA. The proteins, especially the 39 kDa proteins (.alpha. and .beta.) can be used to diagnosis mammals previously or currently infected with the Lyme borreliosis causing agent.
REFERENCES:
patent: 5523089 (1996-06-01), Bergstrom et al.
Simpson et al, Journal of Clinical Microbiology 28: 1329-1337, 1990.
Simpson et al, Journal of Clinical Microbiology 29: 236-243, 1991.
Houghten et al Vaccines 86, pp. 21-25.
Schwan T. G.
Simpson Warren J.
Sidberry Hazel F.
The United States of America as represented by the Department of
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