32142, 21481, 25964, 21686, novel dehydrogenase molecules...

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

Reexamination Certificate

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C435S440000, C435S004000, C435S006120, C435S069100, C435S071100, C435S252300, C435S320100, C536S023200

Reexamination Certificate

active

07045325

ABSTRACT:
The invention provides isolated nucleic acids molecules, designated DHDR nucleic acid molecules, which encode novel DHDR-related dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR gene has been introduced or disrupted. The invention still further provides isolated DHDR proteins, fusion proteins, antigenic peptides and anti-DHDR antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

REFERENCES:
patent: 5750873 (1998-05-01), Dellaporta
patent: 5928923 (1999-07-01), Lal et al.
patent: 6046001 (2000-04-01), Bandman et al.
patent: 2002/0076705 (2002-06-01), Ruben et al.
patent: 1033401 (2000-09-01), None
patent: WO 98/39448 (1998-09-01), None
patent: WO 99/14328 (1999-03-01), None
patent: WO 99/33982 (1999-07-01), None
patent: WO 99/38972 (1999-08-01), None
patent: WO 00/00621 (2000-01-01), None
patent: WO 00/17222 (2000-03-01), None
patent: WO 00/15796 (2000-04-01), None
patent: WO 00/18916 (2000-04-01), None
patent: WO 00/20604 (2000-04-01), None
patent: WO 00/53757 (2000-09-01), None
patent: WO 00/55174 (2000-10-01), None
patent: WO 00/58496 (2000-10-01), None
patent: WO 00/77023 (2000-12-01), None
patent: WO 01/02568 (2001-01-01), None
Ruben et al. Sequence Alignment.
Akbar S. K., et al.,Int. J. Exp. Pathol. 79(5):279-291 (1998).
Akbar, S. M. F., et al.,Eur. J. Clin. Invest. 29(9):786-792 (1999).
Almond, N. et al.,Immunol. Lett. 66(1-3):167-170 (1999).
Andersson, B. et al.,Anal. Biochem. 236(1):107-113 (1996).
Babinet, C. et al.,Science230(4730):1160-1163 (1985).
Blasco, R. et al.,J. Virol. 65(9):4598-4608 (1991).
Bocher, W. O. et al.,Hepatology31(2) :480-487 (2000).
Brown, J. J., et al.,Hepatology31(1):173-181 (2000).
Butel, J. S.,Carcinogenesis21(3) :405-426 (2000).
Cavanaugh, V. J., et al.,J. Virol. 72(4):2630-2637 (1998).
Cavanaugh, V. J., et al.,J. Virol. 71(4) :3236-3243 (1997).
Chou, C. K., et al.,Hepatology16(1) :13-18 (1992).
Cote, P. et al.,Hepatology31(1) :190-200 (2000).
Das, A. K., et al.,J. Biol. Chem. 275(32):24333-24340 (2000).
Douglas, N. J., et al., J. Gen. Virol. 77(pt. 12):3113-3120 (1996).
Farza, H. et al.,Proc. Natl. Acad. Sci U.S.A. 84(5):1187-1191 (1987).
Fenner, F.,FEMS Microbiol. Rev. 24(2):123-133 (2000).
Gripon, P. et al.,J. Med. Virol. 28(3):193-199 (1989).
LeGuerhier, F. et al.,Antimicrob. Agents Chemother. 44(1):111-122 (2000).
Guidotti, L. G., et al.,J. Virol. 69(10):6158-6169 (1995).
Hayashi, Y. et al.,Biochim. Biophys. Acta. 1352(2):145-150 (1997).
Hayashi, K. et al.,Pathol. Int. 50(2): 85-97 (2000).
Heise, T. et al.,J. Virol. 73(1):474-481 (1999).
Hsu, L. et al.,Gene174(2):319-322 (1996).
Ilan, E. et al.,Hepatology29(2): 553-562 (1999).
Kisseljov, F. L.,Biochemistry65(1):68-77 (2000).
Korba, B. E. et al.,Hepatology31(5):1165-1175 (2000).
Koziel, M. J.,Antivir. Ther. 3(Supp 3):13-24 (1998).
Lai, C. H., et al.,Genome Res. 10(5):703-713 (2000).
Larkin, J. et al.,Nat. Med. 5(8):907-912 (1999).
Madden, C. R., et al.,J. Virol. 74(11):5266-5272 (2000).
Niewiesk, S.,Immunol. Lett. 65(1-2):47-50 (1999).
Ohashi, K. et al.,Nat. Med. 6(3):327-331 (2000).
Pasquinelli, C. et al.,Hepatology25(3):719-727 (1997).
Renard, C. A., et al.Res. Virol. 149(3):133-143 (1998).
Sakai, N. et al.,FEBS Lett. 350(2-3):309-313 (1994).
Schat, K. A., et al.,Dev. Comp. Immunol. 24(2-3):201-221 (2000).
Schwarz, M. et al.,J. Clin. Invest. 106(9):1175-1184 (2000).
Seeger, C. et al.,Microbiol. Mol. Biol. Rev. 64(1):51-68 (2000).
Senkevich, T. G. et al.,Science 273(5276):813-816 (1996).
Shimoda, N. et al.,Genomics58(3):219-232 (1999).
Torresi, J. et al.,Gastroenterology118(2 Suppl 1):S83-103 (2000).
Tur-Kaspa, R. et al.,Proc. Natl. Acad. Sci. U.S.A. 83(6):1627-1631 (1986).
Vickery, K. et al.,J. Med. Virol. 58(1):19-25 (1999).
Virgin, H. W. et al.,Curr. Opin. Immunol. 11(4):371-379 (1999).
Wieland, S. F. et al.,J. Virol. 74(9):4165-4173 (2000).
Wiemann, S. et al.,Genome Res. 11(3):422-435 (2001).
Zhang, J. et al.,Biochem. Biophys. Acta. 1435(1-2):184-190 (1999).
Zhao, H. F. et al.,FEBS Lett. 259(1):153-157 (1989).
Results of BLASTN search of nucleic acid patent database using DHDR-4 nucleotide sequence.
Results of BLASTN search of nucleic acid patent database using DHDR-1 nucleotide sequence.
Results of BLASTN search of GenBank database (dbEST) using DHDR-2 nucleotide sequence.
Results of BLASTN search of nucleic acid patent database (FastAlert—N) using DHDR-2 nucleotide sequence.
Results of BLASTN search of GenBank database (nucleic acid) using DHDR-2 nucleotide sequence.
Results of BLASTN search of nucleic acid patent database (PatentDbPreviewNuc) using DHDR-2 nucleotide sequence.
Results of BLASTN search of GenBank database (dbEST) using DHDR-4 nucleotide sequence.
Results of BLASTN search of GenBank database (nucleic acid) using DHDR-4 nucleotide sequence.
Results of BLASTX search of GenBank database (protein) using DHDR-4 predicted polypeptide sequence.
Results of BLASTN search of nucleic acid patent database (PatentDbPreviewNuc) using DHDR-4 nucleotide sequence.
Results of BLASTN search of GenBank database (dbEST) using DHDR-3 nucleotide sequence.
Results of BLASTN search of nucleic acid patent database (FastAlert—N) using DHDR-3 nucleotide sequence.
Results of BLASTX search of protein patent database (FastAlert—P) using DHDR-3 predicted polypeptide sequence.
Results of BLASTN search of GenBank database (nucleic acid) using DHDR-3 nucleotide sequence.
Results of BLASTN search of nucleic acid patent database (PatentDbPreviewNuc) using DHDR-3 nucleotide sequence.
Results of BLASTX search of protein patent database using DHDR-3 predicted polypeptide sequence.
Results of BLASTN search of GenBank database (dbEST) using DHDR-1 nucleotide sequence.
Results of BLASTN search of nucleic acid patent database (FastAlert—N) using DHDR-1 nucleotide sequence.
Results of BLASTN search of GenBank database (nucleic acid) using DHDR-1 nucleotide sequence.
GenSeq Accession No. C09039 for Human secreted protein 5′ EST, SEQ ID No.: 13114.
GenSeq Accession No. X98422 for Human cancer cell derived cDNA #148.
GenSeq Accession No. X99042 for Human validated cancer cell derived cDNA #364.
GenBank Accession No. AI091419 for ow62e03.x1 Soares—NSF—F8—9W—OT—PA—P—S1Homo sapienscDNA clone IMAGE:1651420 3′ similar to WP: T25G12.7 CE07544 DEHYDROGENASE; contains TAR1.t3 MER22 repetitive element; mRNA sequence.
GenBank Accession No. AI741629 for wg28f07.x1 Soares—NSF—F8—9W—OT—PA—P—S1Homo SapienscDNA clone IMAGE:2366437 3′ similar to WP: T25G12.7 CE07544 DEHYDROGENASE; contains TAR1.t3 MER22 repetitive element; mRNA sequence.
GenBank Accession No. AI741640 for wg28g07.x1 Soares—NSF—F8—9W—OT—PA—P—S1Homo sapienscDNA clone IMAGE:2366460 3′ similiar to WP: T25G12.7 CE07544 DEHYDROGENASE; contains TAR1.t3 MER22 repetitive element; mRNA sequence.
GenBank Accession No. AI458236 for tj53e07.x1 Soares—NSF—F8—9W—OT—PA—P—S1Homo sapienscDNA clone IMAGE:2145252 3′ similar to WP: T25G12.7 CE07544 DEHYDROGENASE; contains TAR1.t3 MER22 repetitive element; mRNA sequence.
GenBank Accession No. AI222126 for qh02g04.x1 Soares—NSF—F8—9W—OT—PA—P—S1Homo sapienscDNA clone IMAGE:184542 3′ similar to WP: T25G12.7 CE07544 DEHYDROGENASE; contains TAR1.t3 MER22 repetitive element; mRNA sequence.
GenBank Accession No. AA953672 for oo02e08.s1 Soares—NSF—F8—9W—OT—PA—P—S1.Homo sapienscDNA clone IMAGE:1565030 3′ similar to WP: T25G12.7 CE07544 DEHYDROGENASE; contains TAR1.t3 MER22 repetitive element; mRNA sequence.
GenBank Accession No. AI376903 for tc27f05.x1 Soares—NSF—F8—9W—OT—PA—P

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