3′-prodrugs of 2′-deoxy-β-L-nucleosides

Details 3′-prodrugs of 2′-deoxy-β-L-nucleosides 3′-prodrugs of 2′-deoxy-β-L-nucleosides

2005-04-05

2005-04-05

Owens, Howard V (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S042000, C536S028500

Reexamination Certificate

active

06875751

ABSTRACT:
The present invention relates to compounds, compositions and methods for the treatment of a host infected with a hepatitis B virus. Specifically, compound and compositions of 3′-esters of 2′-deoxy-β-L-nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents. Compound and compositions of 3′,5′-diesters of 2′-deoxy-β-L-nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents, are also disclosed.

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