3-Trehalosamine compounds

Details 3-Trehalosamine compounds 3-Trehalosamine compounds

1979-09-17

1981-06-30

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424181, 435 72, 435100, 435 84, 435253, 536 18, 536115, 536116, 536120, A61K 3171, C07H 506

Patent

active

042764122

ABSTRACT:
Novel antibiotic 3-trehalosamine (U-59,834) producible in a fermentation under controlled conditions using the new microorganism Nocardiopsis trehalosei sp. nov., NRRL 12026.
This antibiotic is active against Gram-positive bacteria, for example, Staphylococcus aureus, Bacillus subtilis, and Diplococcus pneumoniae. Thus, 3-trehalosamine can be used in various environments to eradicate or control such bacteria.
Antibiotic 3-trehalosamine can be shown by the following structural formula: ##STR1##

REFERENCES:
Arcamone et al., "Gazz. Chim. Ital.," vol. 87, 1957, pp. 896-902.
Wolfrom, "Advances in Carbo. Chem.," vol. 18, 1963, pp. 219-221.
Uramoto et al., "Jour. Antibiotics," vol. 20, 1967, pp. 236-237.
Hanessian et al., "Jour. Antibiotics," vol. 25, 1972, pp. 683-684.
Hough et al., "J.C.S. Perkin I," 1973, pp. 287-290.
Naganawa et al., "J. Antibiotics," vol. 27, pp. 145-146, 1974.
Wright et al., "J. Chem. Soc. Chem. Commun.," 1977, pp. 710-712.

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