3-thiazolomethyl cephalosporins as antibiotics

Details 3-thiazolomethyl cephalosporins as antibiotics 3-thiazolomethyl cephalosporins as antibiotics

1984-12-24

1987-05-12

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

548159, 540227, A61K 31545, C07D50146

Patent

active

046650660

ABSTRACT:
7.beta.-[2-(2-Aminothiazol(oxazol)-4-yl)-2-oximinoacetamido]-3-(thiazolium or substituted thiazolium-3-yl)methyl-3-cephem-4-carboxylates and the correspondingly substituted 1-oxadethia and 1-carbadethia 3-cephem compounds are potent antibacterials useful in a therapeutic method for treating bacterial diseases. Also provided are pharmaceutical formulations of these thiazolium-substituted compounds and intermediates useful in the preparation thereof.

REFERENCES:
patent: 4165430 (1979-08-01), Bradshaw et al.
patent: 4168309 (1979-09-01), Ayres et al.
patent: 4275062 (1981-06-01), Brewer et al.
patent: 4425340 (1984-01-01), Teraji et al.
patent: 4476123 (1984-10-01), Labeeuw et al.
patent: 4500526 (1985-02-01), Imae et al.
patent: 4507487 (1985-03-01), Kamachi et al.
Fujimoto et al., "Cephalosporin Antibiotics . . . ", Chem. Abst. 103: 178066j, (1984).
McOmie, J. F. W., Protective Groups in Organic Chemistry, Plenum Press (1973), New York, pp. 192, 193, 204.
Fujimoto, K., et al., "Annual Report of Sankyo Research Laboratories", vol. 36, Dec. 1984, pp. 93-113.
Derwent Abstract 85-130958/22.

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