Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-04-20
1978-07-25
Coughlan, Jr., Paul M.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260301, 2603067R, 542442, 542443, 542446, C07D27714
Patent
active
041028880
ABSTRACT:
This invention relates to novel 8-aza-9-oxo-11-thia-, -11-oxothia-, and -11-dioxothia-prostanoic acid compounds, salts, and derivatives thereof and also to processes for the preparation of such compounds. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the treatment of certain autoimmune diseases, and in preventing thrombus formation.
REFERENCES:
patent: 3853902 (1974-12-01), Raasch
patent: 4059587 (1977-11-01), Smith et al.
Cragoe, Jr. Edward J.
Lee Ta-jyh
Smith Robert L.
Anderson, Jr. Rudolph J.
Arther Thomas E.
Coughlan, Jr. Paul M.
Merck & Co. , Inc.
Westlake, Jr. Harry E.
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