3-Thia-4-arylquinolin-2-one derivatives as smooth muscle...

Details 3-Thia-4-arylquinolin-2-one derivatives as smooth muscle... 3-Thia-4-arylquinolin-2-one derivatives as smooth muscle...

2006-02-21

2006-02-21

Raymond, Richard L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C544S062000, C544S128000, C544S333000, C544S363000

Reexamination Certificate

active

07002015

ABSTRACT:
This invention describes compounds of Formula (I) which are modulators of potassium channels and are useful for treating conditions affected by abnormal potassium channel activity including erectile dysfunction and irritable bowel syndrome.

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patent: 2002371078 (2002-12-01), None
patent: WO 02/026713 (2002-04-01), None
P. Hewawasam, et al, “4-Aryl-3-(Hydroxyalkyl)Quinolin-2-Ones: Novel Maxi-K Channel Opening Relaxants of Corporal Smooth Muscle Targeted for Erectile Dysfunction,” J. Med. Chem., 46, pp. 2819-2822, 2003.

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