Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-07-10
1992-09-29
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540222, 540225, C07D50132, A61K 31545
Patent
active
051514176
ABSTRACT:
3-Substituted vinyl cephalosporin derivatives represented by the following formula: ##STR1## wherein R.sup.1 represents a hydroxyl or lower alkoxyl group, X represents a nitrogen atom or a group represented by the formula --CH.dbd., R.sup.2 represents a carboxyl group or a carboxyl group protected with a protecting group, and R.sup.3 is as defined herein, and pharmaceutically acceptable salts thereof are potent antibacterial agents. Processes for their preparation, intermediates in such processes, and antibacterial compositions containing them as active ingredients are also described.
REFERENCES:
patent: 4520193 (1985-05-01), Berge et al.
patent: 4639448 (1987-01-01), Takaya et al.
patent: 4731362 (1988-03-01), Damashima et al.
patent: 4874856 (1989-10-01), Iimula et al.
Katsu Kanemasa
Komatu Yuuki
Nakamura Takaharu
Negi Shigeto
Sasho Manabu
Eisai Co. Ltd.
Rizzo Nicholas S.
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