3-Substituted propanoic acid derivatives and pharmaceutical comp

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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Details

260468K, 260471R, 260473P, 260476R, 260487, 260488R, 260514K, 424311, A01N 924, C07C 6138

Patent

active

040270360

ABSTRACT:
The invention provides 3-(2-formyl-3-hydroxy-5-oxocyclopent-1-enyl)-propanoic acid and derivatives thereof having anti-thrombotic activity coupled with low toxicity. Also provided is a method for preparing such compounds by subjecting a 3-[3-hydroxy-5-oxo-2-(.beta.-styryl)cyclopent-1-enyl]-propanoic acid or derivative thereof to oxidative cleavage.

REFERENCES:
patent: 3657316 (1972-04-01), Samuelson
patent: 3810936 (1974-05-01), Miyano

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