Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1977-03-02
1978-07-11
Thomas, Jr., James O.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560 55, 560106, 560177, 560228, 560231, 560 73, 260514K, 424305, 424311, 424317, C07C 7946, A01N 924, C07C 6976
Patent
active
041003500
ABSTRACT:
The invention provides 3-(2-formyl-3-hydroxy-5-oxocyclopent-1-enyl)-p ropanoic acid and derivatives thereof having anti-thrombotic activity coupled with low toxicity. Also provided is a method for preparing such compounds by subjecting a 3-[3-hydroxy-5-oxo-2-(.beta.-styryl)cyclopent-1-enyl]-propanoic acid or derivative thereof to oxidative cleavage.
REFERENCES:
patent: 3687811 (1972-08-01), Colton et al.
patent: 3696144 (1972-10-01), Miyano
patent: 3732267 (1973-05-01), Miyano
patent: 3935240 (1976-01-01), Mallion
Boot et al., Prostaglandins, 8(5), 439-446, 1974.
Dawson William
Foulis Michael John
Gutteridge Norman James Albert
Smith Colin William
Breitenstein G. T.
Lammert Steven R.
Lilly Industries Ltd.
Smith Everet F.
Thomas, Jr. James O.
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