3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)ceph

Details 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)ceph 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)ceph

1992-07-22

1993-12-21

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514210, C07D48704, A61K 31435

Patent

active

052722651

ABSTRACT:
1-Carba(1-dethia)cephem antibacterial agents possessing a 3-(substituted or unsubstituted)thiazolo group are provided. Further provided is a method for treating bacterial infections in man and other animals and a pharmaceutical formulation utilizing said 1-carba(1-dethia)cephems.

REFERENCES:
patent: 5077287 (1991-12-01), Ternansky
patent: 5089610 (1992-02-01), Ternansky
patent: 5179088 (1993-01-01), Hornback et al.
R. A. Firestone et al., J. of Medicinal Chemistry, 1977, vol. 20, No. 4, pp. 551-556.
Guthikonda et al., J. Am. Chem. Soc., 96, No. 24, pp. 7584-7585 (1974).
J. F. Peyronel et al., "Recent Advances in the Chemistry of .beta.-lactam Antibiotics", Royal Society of Chemistry, London, 1985; Publ. No. 52, p. 336.

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