3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline deriva

Details 3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline deriva 3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline deriva

1994-07-20

1996-04-30

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D48704, A61K 31505

Patent

active

055126774

ABSTRACT:
The present invention provides a novel series of 3-substituted methyl-2,5-dihydroimidazo 1,2-c!quinazoline compounds. These compounds are found useful as an active ingredient for the treatment of hypertension and dysuria.

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patent: 5158953 (1992-10-01), Chern et al.
Ji-Wang Chern, et al., "Studies On Quinazolines, 3:1 Novel And Efficient . . . ", Biorganic & Medicinal Chemistry Letters, vol. 1, No. 11, pp. 571-574, 1991.
Narihito Seki, et al., "Electrical and Mechanical Properties of the Capsular . . . ", Br. J. Pharmacol, (1988), 93, 702-714.
Yamanouchi, et al., article from Drug of the Future, (1989), p. 400.
Virginia Bogert Schatz, "Isoterism and Bio-isosterism as Guides to Structural Variations", Medicinal Chemistry, Interscience Publishers, Inc., 1960, pp. 72-78, edited by Alfred Burger.

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