3-Substituted isotryptamine derivatives and process for their pr

Details 3-Substituted isotryptamine derivatives and process for their pr 3-Substituted isotryptamine derivatives and process for their pr

1974-04-12

1976-01-06

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029355, 26032612R, 26032614R, 424274, C07D20914

Patent

active

039312305

ABSTRACT:
The present invention concerns compounds of Formula I ##SPC1##
wherein R.sub.1 is hydrogen, lower alkyl, aralkyl; R.sub.2 is hydrogen, lower alkyl, lower alkoxy, halogen, trifluoromethyl, cyano, nitro, and the like; R.sub.3 is lower alkyl; ##EQU1## (where R.sub.4 and R.sub.5 are lower alkyl), ##EQU2## (where R.sub.6 is hydrogen, lower alkyl, aryl, acetamido and R.sub.7 is lower alkyl), ##SPC2##
(where R.sub.8 and R.sub.9 are hydrogen or lower alkyl), --CH(SO.sub.2 C.sub.6 H.sub.5).sub.2, ##SPC3## ##EQU3## (where R.sub.10 is hydrogen, CN, acyl), ##EQU4## (where R.sub.11 and R.sub.12 are lower alkyl), --SO.sub.2 C.sub.6 H.sub.5, --CONH.sub.2, --CO.sub.2 R.sub.13 (where R.sub.13 is lower alkyl), ##EQU5## (R.sub.14 and R.sub.15 are lower alkyl). These compounds are useful as sedatives and antiaggression agents.

REFERENCES:
patent: 2883394 (1959-04-01), Schindler
patent: 3781299 (1973-12-01), Yamamoto

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