3-substituted indoles and derivatives thereof as therapeutic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S418000, C548S251000, C548S484000

Reexamination Certificate

active

07074814

ABSTRACT:
The present invention provides indoles of Formula I:wherein R1and R2have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula I.

REFERENCES:
patent: 3954748 (1976-05-01), Thominet
patent: 4675332 (1987-06-01), Connor et al.
patent: 4703053 (1987-10-01), Connor et al.
patent: 4764525 (1988-08-01), Connor et al.
patent: 4767776 (1988-08-01), Connor et al.
patent: 4800211 (1989-01-01), Tischler et al.
patent: 4910317 (1990-03-01), Connor et al.
patent: 4931459 (1990-06-01), Connor et al.
patent: 5208253 (1993-05-01), Boschelli et al.
patent: 5426113 (1995-06-01), Low
patent: 5468898 (1995-11-01), Huang et al.
patent: 5565488 (1996-10-01), Braunlich et al.
patent: 5731317 (1998-03-01), Lu et al.
patent: 6274535 (2001-08-01), Feurer et al.
patent: 6444613 (2002-09-01), Feurer et al.
patent: 6471997 (2002-10-01), Breton et al.
patent: 1 227 084 (2002-07-01), None
Boschelli, et al, “Inhibition of E-Selectin-, ICAm-1, and VCAM-1-Mediated Cell Adhesion by Benzo[b]thiophene-, Benzofuran-, Indole-, and Naphthalene-2-carboxamides: Identification of PD 144795 as an Antiinflammatory Agent”, J. Med. Chem., 1995, vol. 38, pp. 4597-4614.
David T. Connor, et al, “Novel Benzothiophene-, Benzofuran-, and Naphthalenecarboxamidotetrazoles as Potential Antiallergy Agents”, J. Med. Chem., 1992, vol. 35, pp. 958-965.
Pakray, et al, “The Synthesis of Dimethoxyl[1]benzothieno[2,3-c]quinolines”, Dep. of Chem, Univ. of S. FL, Sep.-Oct. 1986, pp. 1571-1577.
Oremek, et al, “Synthese von substituierten Benzo [b]thiophenen”, Liebigs Ann. Chem., 1980 pp. 1424-1427.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

3-substituted indoles and derivatives thereof as therapeutic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-substituted indoles and derivatives thereof as therapeutic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-substituted indoles and derivatives thereof as therapeutic... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3553568

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.