3-substituted carbacepem compounds having antibacterial effect

Details 3-substituted carbacepem compounds having antibacterial effect 3-substituted carbacepem compounds having antibacterial effect

1985-02-19

1987-02-03

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514256, 514269, 514299, 544180, 544216, 544242, 544298, 544319, 546183, A61K 3153, C07D25100, C07D25300

Patent

active

046409190

ABSTRACT:
Carbacephem compounds represented by the formula: ##STR1## [wherein R.sub.1 is a lower alkylsulfonyloxy, unsubstituted or substituted arylsulfonyloxy, azido, cyano, carbamoyloxy, unsubstituted or substituted heterocyclic thio ("heterocyclic" means a 5- or 6-membered heterocyclic group having 1 to 4 O, S or N atoms), unsubstituted or substituted lower alkylthio, or unsubstituted or substituted arylthio group; R.sub.2 and R.sub.3 are groups frequently used in the cephalosporin chemistry] have strong antibacterial activity against Gram-positive and Gram-negative bacteria, and are useful for curing various infections.

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