3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes

Details 3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes 3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes

1975-08-21

1976-04-20

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424250, C07D45102, C07D48708

Patent

active

039519805

ABSTRACT:
Twelve analogs of diethylcarbamazine as prepared by acylation of 3- and 8-methyl-3,8-diazabicyclo[3.2.1]octane, 2-methyl-2,5-diazabicyclo[2.2.2]octane, and 2-methyl-2,5-diazabicyclo[2.2.1]heptane with diethylcarbamyl chloride, ethyl chloroformate, ethyl isocyanate, and cyclohexanecarbonyl chloride. These compounds are formally derived from diethylcarbamazine in possessing two- or one-carbon bridges over the piperazine ring. The compounds have utility as antifilarial agents and as bronchodilators.

REFERENCES:
patent: 3905979 (1975-09-01), Henry et al.
Giorgio Cignarella et al., Journal of Medicinal Chemistry, Vol. 6, pp. 385-387, (1963).

Affiliated with

Also associated with

Rating

3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-Substituted-8-methyl-3,8-diazabicyclo[3.2.1]octanes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1587257