3-Substituted-6-(1'-hydroxyethyl)-7-oxo-1-azabicyc lo[3.2.0]-hep

Details 3-Substituted-6-(1'-hydroxyethyl)-7-oxo-1-azabicyc lo[3.2.0]-hep 3-Substituted-6-(1'-hydroxyethyl)-7-oxo-1-azabicyc lo[3.2.0]-hep

1980-11-14

1982-08-31

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260239A, 2602452T, 2602453, 424258, 424263, 424269, 424270, 424272, 424273B, 424274, 542413, 542443, C07D48704

Patent

active

043473679

ABSTRACT:
Disclosed are 3-substituted-6-(1'-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-ca rboxylic acids having the structure: ##STR1## wherein R.sup.8 is, inter alia, selected from the group consisting of hydrogen, alkyl, alkenyl, aryl and aralkyl. Such compounds as well as their pharmaceutically acceptable O- and carboxyl derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 4234596 (1980-11-01), Christensen et al.

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