Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-05-30
1976-07-13
Jiles, Henry R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424248, 424250, 424267, 424269, 260246B, 2602471M, 2602472A, 260268C, 260268H, 26029364, 26029369, C07D40302
Patent
active
039693660
ABSTRACT:
Compounds of the following formula and their pharmaceutically acceptable salts ##SPC1##
Wherein R.sub.1 and R.sub.4 are the same or different and are each a five or six membered N containing heterocycle attached at an available N atom; R.sub.2 is hydrogen, alkyl, trifluoromethyl, phenyl, benzyl, --(CH.sub.2).sub.n --R.sub.4 or --(CH.sub.2).sub.n --N(alkyl).sub.2 ; R.sub.3 is hydrogen, halogen, nitro, trifluoromethyl, alkyl, alkoxy, or alkylthio; and n is an integer from 1 to 4; are disclosed. These compounds are useful as anti-inflammatory agents.
REFERENCES:
patent: 3308131 (1967-03-01), McKusick
patent: 3376306 (1968-04-01), Roland
Vogt Berthold Richard
Wade Peter C.
Davis Stephen B.
E. R. Squibb & Sons Inc.
Jiles Henry R.
Levinson Lawrence S.
Ramsuer R. W.
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