Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-04-18
2000-10-03
Seaman, D. Margaret
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514340, 514343, 546193, 546194, 5462681, 5462764, A61K 3144, C07D47102, C07D21330
Patent
active
061273864
ABSTRACT:
Novel 3-pyridyloxymethyl heterocyclic ether compounds of the formula: ##STR1## or the pharmaceutically-acceptable salts or prodrugs thereof are selective and potent ligands at neuronal nicotinic cholinergic channel receptors, and are effective in controlling synaptic transmission. Key intermediates and processes using this key intermediates to produce compounds of formula I with the variables defined in the specification are also described.
REFERENCES:
patent: 5629325 (1997-05-01), Lin
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M. Davidson et al., Current Research Alzheimer Therapy, "Cholinergic Agonists in Alzheimer's Disease Patients", E. Giacobini ans R. Becker, eds., Taylor & Francis, New York, (1988), pp. 333-336.
Bai Hao
He Yun
Holladay Mark W.
Li Yihong
Lin Nan-Horng
Abbott Laboratories
Pope Lawrence S.
Seaman D. Margaret
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