3-pyridyl compounds and use as thromboxane synthetase inhibitors

Details 3-pyridyl compounds and use as thromboxane synthetase inhibitors 3-pyridyl compounds and use as thromboxane synthetase inhibitors

1985-08-21

1988-05-17

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514332, 514333, 514336, 514341, 546256, 546263, 546266, 546278, 546283, 546284, 546339, 546340, 546342, 546344, A61K 3144, A61K 31455, C07D21350, C07D40112

Patent

active

047451203

ABSTRACT:
The present invention relates to new pyridines substituted in the 3-position, of the formula ##STR1## and to a process for their preparation. The compounds bring about specific inhibition of thromboxane synthetase and can thus be used as medicaments.

REFERENCES:
patent: 4271176 (1981-06-01), Tanouchi et al.
patent: 4317828 (1982-03-01), Tanouchi et al.
patent: 4427680 (1984-01-01), Tanouchi et al.
Glossary of Chemical Terms, Hampel and Hawley, Editors, p. 6.
Tanouchi et al., Highly Selective . . . Pyridine Derivatives, J. Med. Chem., 1981, 24, 1149-1155.

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