3-Pyridyl-5-alkoxy-pyrazole derivatives and pharmaceutical compo

Details 3-Pyridyl-5-alkoxy-pyrazole derivatives and pharmaceutical compo 3-Pyridyl-5-alkoxy-pyrazole derivatives and pharmaceutical compo

1983-07-12

1985-07-02

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546279, A61K 3144, C07D40104

Patent

active

045268959

ABSTRACT:
The invention relates to new 3-pyridyl-5-alkoxy-pyrazole derivatives of the following formula: ##STR1## wherein R.sub.1 represents a 4-pyridyl, 3-pyridyl or 2-pyridyl group which is unsubstituted or which may be substituted with one or two lower alkyl groups; R.sub.2 represents a hydrogen atom or a lower alkyl group; and R.sub.3 represents a lower alkyl group, a phenyl group or an aralkyl group; and the acid addition salts thereof. The derivatives may be prepared by alkylation of a 3-pyridyl-5-pyrazolone. The derivatives are medicinally useful, particularly for the treatment of cardiac deficiency.

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