Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-08-08
2006-08-08
Bernhardt, Emily (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S253060, C544S360000, C544S363000, C544S364000
Reexamination Certificate
active
07087609
ABSTRACT:
The present invention provides piperazinyl phenylethyl amides and related derivatives having the general Formula Iwherein R1, R2, R3, R4, R5, R6, A and B are as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said piperazinyl phenylethyl amides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain, and anxiety.
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Chen Jie
Sun Li-Qiang
Wu Yong-Jin
Algieri Aldo A.
Bernhardt Emily
Bristol--Myers Squibb Company
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