3-Propenyl derivatives of cephalosporin, compositions and their

Details 3-Propenyl derivatives of cephalosporin, compositions and their 3-Propenyl derivatives of cephalosporin, compositions and their

1976-07-29

1978-06-13

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 16, 544 30, 544 28, 544 22, 542416, 560 29, 560 39, A61K 31545, C07D50124

Patent

active

040949788

ABSTRACT:
3-(3-hydroxyprop-1-(t)-enyl)-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids; 3-(3-carbamoyloxyprop-1-(t)-enyl)-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids; and 3-[3-(N-substituted carbamoyloxy)prop-1-(t)-enyl]-7.beta.-(.alpha.-substituted acetamido)-ceph-3-em-4-carboxylic acids and derivatives and salts thereof and process for preparing such compounds. The compounds are useful as antibacterials and are active against a wide variety of gram positive and gram negative bacteria.

REFERENCES:
patent: 3929780 (1975-12-01), Weir
patent: 3983113 (1976-09-01), Beeby
patent: 3994884 (1976-11-01), Weir
patent: 4012380 (1977-03-01), Spry

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