3-phenylpropionic acid derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S207000, C548S209000, C548S212000

Reexamination Certificate

active

11332708

ABSTRACT:
The invention relates to new compounds, 3-phenylpropionic acid derivatives of formula (I) wherein W represents COOH group or its bioisosters, or —COO—C1–C4-alkyl group; Y represents NH, N—C1–C10-alkyl, O, or S; X represents O, S, NH, N—C1–C10-alkyl, N-aryl, NSO2—C1–C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R1to R8each independently represents hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof. The compounds are the ligands of PPAR-gamma receptor and are useful as medicaments

REFERENCES:
patent: 1184366 (2002-03-01), None
patent: WO-95/25107 (1995-09-01), None
patent: WO97/31907 (1997-09-01), None
patent: WO01/17994 (2001-03-01), None
patent: WO03/011814 (2003-02-01), None
patent: WO03/011834 (2003-02-01), None
International Search Report and Written Opinion, dated Apr. 18, 2004 (6 pages).

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