3-Oxyiminomethyl-cephalosporins

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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Details

260240G, 424246, C07D50146, C07D50142

Patent

active

039870391

ABSTRACT:
An antibacterial 7-protected amino-3-oxyiminomethyl-3-cephem-4-carboxylic acid is prepared by the reaction of a 7-protected amino-3-formyl-3-cephem-4-carboxylic acid or its reactive derivatives with a hydroxylamine compound or its reactive derivatives, the process being more suitable for large scale production when coupled with fermentative production of a 3-hydroxymethyl-3-cephem-4-carboxylic acid followed by its direct oxidation.

REFERENCES:
patent: 3674784 (1972-07-01), Webber
patent: 3840533 (1974-10-01), Dolfini et al.

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