Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent
Patent
1976-08-16
1978-08-29
Daus, Donald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Chalcogen in the nitrogen containing substituent
C07D50136
Patent
active
041105354
ABSTRACT:
Ureido cephalosporin derivatives of the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl, a salt forming ion, or the group ##STR2## R.sub.1 is hydrogen, lower alkyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, phenyl, phenyl-lower alkyl, substituted phenyl or phenyl-lower alkyl, or certain heterocyclic groups; R.sub.2 is hydrogen or lower alkyl; R.sub.3 is hydrogen or methoxy; R.sub.4 is hydrogen, halogen, lower alkyl, or lower alkoxy; R.sub.5 is hydrogen or lower alkyl; R.sub.6 is lower alkyl, phenyl, or phenyl-lower alkyl; are disclosed. These compounds are useful as antibacterial agents.
REFERENCES:
patent: 3860591 (1975-01-01), Breuer
patent: 3892737 (1975-07-01), Ochiai et al.
patent: 3912728 (1975-10-01), Crooij et al.
patent: 3954757 (1976-05-01), Arya et al.
patent: 3978051 (1976-08-01), Dolfini
patent: 3979408 (1976-09-01), Trani
patent: 3989693 (1976-11-01), Dolfini
patent: 3989697 (1976-11-01), Dolfini
patent: 4000134 (1976-12-01), Dolfini
Pollak et al. Monatshefte fur Chemie 1972, vol. 103, pp. 1591-1603.
Verge et al. Chem. Abst. 1975, vol. 83, No. 10079k.
Breuer Hermann
Treuner Uwe D.
Daus Donald G.
Davis Stephen B.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Smith Merle J.
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