Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1979-01-25
1983-11-15
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
2602453, C07D49804, A61K 3142
Patent
active
044155840
ABSTRACT:
Compounds of the formula (II): ##STR1## wherein R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms, CO.sub.2 R.sub.2 is a carboxyl group, a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable esterified carboxyl group, are useful for their .beta.-lactamase inhibitory activity and to synergize the antibacterial activity of penicillins and cephalosporin.
REFERENCES:
patent: 4036969 (1977-07-01), Stirling
Merck Index, p. 1005.
Melmon, "Clinical Pharmacology", p. 47.
"Nomenclature of Organic Chemistry", 1979 Edition 1. U.P.A.C., pp. 202, 206.
Naming Organic Compounds, 2nd Edition, Banks, p. 191.
An Introduction to Chemical Nomenclature, 4th Ed., Cahn, p. 98.
Condensed Chemical Dictionary, 9th Edition, p. 16.
Organic Chemistry, vol. 1 (FINAR), p. 222.
"Organic Chemistry, 2nd Edition 1964", Cram et al., pp. 90-91.
Kingzett's Chemical Encyclopedia, 9th Edition, p. 18.
Beecham Group Limited
Berch Mark L.
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