3-oxaprostaglandins

Details 3-oxaprostaglandins 3-oxaprostaglandins

1985-03-25

1986-10-14

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Silicon containing

C07F 718

Patent

active

046174117

ABSTRACT:
This invention relates to novel 3-oxa-15-desoxy-16-hydroxy-16-alkyl prostaglandins of the E.sub.2 series and the 5,6-acetylene derivatives thereof. These compounds are useful for their gastric antisecretory, cytoprotective, antiulcer, and antihypertensive activity. In addition the invention also discloses certain novel trialkylsilyl acetylenic intermediates.

REFERENCES:
patent: 4254285 (1981-03-01), Wissner

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