3-Oxa-D-prostaglandins for lowering IOP

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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Details

514573, 514913, A61K 31215, A61K 3119

Patent

active

057008353

ABSTRACT:
Compositions containing 3-Oxa-D-prostaglandins and methods of their use in treating glaucoma or ocular hypertension are disclosed.

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Sharif, Emedastine: A Potent, High Affinity Histamine H.sub.1 --Receptor-Selective Antagonist for Ocular Use: Receptor Binding andSecond Messenger Studies, Journal of Ocular Pharmacology, vol. 10, No. 4, pp. 653-664 (1994).
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Jagabandhu Das et al., 9,11-Epoxy-9-homoprosta-5-enoic acid analogues as thromboxane A2 receptor antagonists,, .Med. Chem., vol. 33, pp. 1741-1748 (1990).
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