3-Oxa carbinol prostaglandin analogs

Details 3-Oxa carbinol prostaglandin analogs 3-Oxa carbinol prostaglandin analogs

1978-09-12

1979-06-12

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424331, C07C17700

Patent

active

041580184

ABSTRACT:
Disclosed are trans, 3-oxa carbinol analogs of prostaglandin E.sub.1 represented by the formula: ##STR1## wherein R is n-alkyl of 4-6 carbon atoms, cycloalkyl of 5 to 7 carbon atoms or 1,1-dimethylalkyl of 6 to 8 carbon atoms. Particular compounds corresponding to the above formula are variously useful as antithrombotic agents due to their ability to inhibit platelet aggregation, bronchodilators, inhibitors of gastric secretion and anti-hypertensive agents.

REFERENCES:
patent: 3636120 (1972-01-01), Pike

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